Vascular Biomechanics and Mechanobiology
The Wagenseil lab studies cardiovascular mechanics, focusing on cardiovascular development, extracellular matrix proteins, and microstructurally-based constitutive modeling. This research is critical for improving clinical interventions for elastin-related diseases and designing advanced protocols for the construction of tissue-engineered blood vessels.
Research Areas
Biomechanics & Mechanobiology
Investigates how mechanobiology and biomechanics of the large arteries contribute to normal cardiovascular function during development and abnormal function in disease.
Biomedical & Biological Imaging
Utilizes advanced imaging and computational methods to study cellular and extracellular matrix changes in wall structure and quantify transport through the aortic wall.
Biomedical, Bio-inspired, and Bio-derived Materials
Focuses on the mechanical properties of developing aorta and how extracellular matrix proteins are optimizied for mechanical function. The infromation may be applied to designing tissue-engineered blood vessels.
Cardiovascular Engineering
Studies the mechanical behavior of large, elastic arteries, focusing on cardiovascular development, extracellular matrix proteins, and microstructurally-based constitutive modeling.
Funding
