Wagenseil Vascular Mechanics Laboratory
Welcome to the Wagenseil Vascular Mechanics Laboratory. We focus on the mechanical behavior of large, elastic arteries during development and disease. We are interested in how the arterial wall remodels to maintain appropriate mechanical properties for heart function.
About Prof. Jessica Wagenseil
My research seeks to advance our understanding of vascular mechanics, specifically the interplaybetween the mechanical properties of (biomechanics) and the effects of mechanical forces on(mechanobiology) the large, elastic arteries, such as the aorta. Advances in vascular biomechanicsand mechanobiology are critical to diagnose, prevent, and treat diseases that cause narrowing,dilation, or stiffening of the aorta, including supravalvular aortic stenosis, thoracic aorticaneurysms, and hypertension.
About the Lab
Researcher in vascular biomechanics and mechanobiology that has been funded by NIH, NSF, and private foundations. Dedicated department, school, and university citizen with extensive service and leadership in research administration, faculty advancement, and equity, diversity, and inclusion.
Research Focus
Biomechanics & Mechanobiology
The laboratory examines how mechanobiology and biomechanics of the large arteries contribute to normal cardiovascular function during development and abnormal function in disease.
Biomedical & Biological Imaging
Research utilizes imaging and computational methods to quantify transport through the aortic wall and study cellular and extracellular matrix changes.
Biomedical, Bio-inspired, and Bio-derived Materials
Work focuses on the mechanical properties of bio-artificial tissues and designing improved protocols for building tissue-engineered blood vessels.
Cardiovascular Engineering
Studies the mechanical behavior of large, elastic arteries, focusing on cardiovascular development, extracellular matrix proteins, and microstructurally-based constitutive modeling.
Join the Wagenseil Vascular Mechanics Laboratory
The laboratory welcomes anyone interested in studying vascular biomechanics and mechanobiology in development and disease, focusing on how the mechanical behavior of large, elastic arteries contributes to normal cardiovascular function and abnormal function in disease.